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Commentary
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Timeline for Kocyigit Ozcan Family Clusters in Dogubeyazit

Recombinomics Commentary

January 22, 2006

Below is a summary of the Kocyigit/Oscan cluster.  All members from Dogubeyazit and are likely involved in human-to-human H5N1 transmission, as well as cluster-to-cluster H5N1 transmission. Disease onset dates are from media reports or extrapolation from hospital admission dates.

Sagdic Village

Kocyigit family
Zeki Kocyigit (father)
Marifet Kocyigit (mother)  related to Ozcan1
Mehemet Ali Kocyigit (14M) deceased January 1, H5N1+
Fatma Kocyigit (15F) deceased January 5, H5N1+
Hulya Kocyigit (11F) deceased January 6, H5N1 +
Ali Hasan Kocyigit admitted Van January 1, released

Ozcan1 family cousins to Kocyigit
Samil Ozcan (father) 
Refika Ozcan (33F - mother) admitted to Van January 6, released
Aysegul Ozcan (9F) admitted to Van January 4 H5N1 +
Yusuf Ozcan (3M) admitted to Van January 4 H5N1 +
Hakan Ozcan (15) admitted to Van January 5, released
Hatice Ozcan (15F) admitted to Van January 4, released, attended Fatma burial
Mehemet Ozcan (13M) admitted to Van January 5, released
Ahmet Ozcan (11M) admitted to Van January 6, released
Mustafa Ozcan (6M) admitted to Van January 6, released
Rumeysa Ozcan (1) admitted to Van January 6, released
Rukiye Ozcan admitted to Van January 6, released

Ozcan2 family  cousins to Ozcan1
Mehemet Emin Ozcan (father)
Fatma Ozcan (14F) deceased January 15 H5N1+
Mehemet Ozcan (5M) admitted to Van January 15 H5N1+

Sulucam village

Ozcan3 family
Yavuz Ozcan (3M) admitted to Van January 14
Volkan Ozcan (2M) admitted to Van January 14

unknown village

Ozcan4 family
Six Ozcans related to Fatma Ozcan admitted to Igdir State Hospital January 20

Timeline

January 20 Six Ozcans related to Fatma Ozcan transferred to Igdir State Hospital

January 16 WHO update on Mahamet Ozcan (5M) and Fatma Ozcan (14F).  Report gives disease onset dates and hospitalization.  Fails to mention prior disease in Ozcan cousins and Kocyigit cousins. Fatma Ozcam (14F) buried. Hatice Ozcan (15F) at burial

January 15 Fatma Ozcan (14F) dies

January 14 Yavaz Ozcan (3M) and Volkan Ozcan (2M) hospitalized in Van

January 13 Yavaz Ozcan (3M) and Volkan Ozcan (2M) develop symptoms

January 11 Mahamet and Fatma Ozcan hospitalized in Van

January 9 WHO update on Ozcan (9F) and Ozcan (3M) indicates they are siblings.  No disease onset dates or relationships to other patients given.

January 7 WHO update confirms Muhamet Ali Kocyigit (14M) and Fatma Kocyigit (15F) are H5N1 positive, Hulya Kocyigit (12F) has died, and Kocyigit (6M) hospitalized.  Mentions 30 patients being tested, including many from Dogubeyitz.  No disease onset dates from Kocyigit siblings and no mention of relationship to Ozcans in the hospital.

January 6 Rifica Ozkan (33F), Hakan Ozcan (15M), Rukiye Ozcan hospitalized in Van

January 5 WHO Turkey report indicates Mehamet Kocygit (14M) was hospitalized and died on January 1 and Fata Kocyigit (15F) died January 5 after hospitalized January 1 in Van.  Rumeysa Ozcan (1F), Mustafa Ozcan (6F), Ahmat Ozcan (11M), Mehemet Ozcan (13M) hospitalized in Van. Rifica Ozkan (33F), Hakan Ozcan (15M), Rukiye Ozcan develop symptoms

January 4 Mehemet (5M) and Fatma Ozcan (14F) develop symptoms. Hatice Ozcan (15F), Aysegul Ozcan (9F), Yusuf Ozcan (3M) admitted to Van. Aysegul (9F) and Yusuf (5M) placed in ICU. Rumeysa Ozcan (1F), Mustafa Ozcan (6F), Ahmat Ozcan (11M), Mehemet Ozcan (13M) develop symptoms

January 1 Ducks began dying in Ozcan2 flock.  Mahamet (5M) and Fatma (14F) slaughter duck. Mehemet Ali (14M), Fatma (15F), Hulya (12F), Ali Hasan Kocyigit (6M) transferred to Van from Dogubeyitz hospital. 3 oldest siblings unconscious. Hatice Ozcan develops symptoms

December 30 Mehemet Ali (14M), Fatma (15F), Hulya (12F), Hasan Ali Kocyigit admitted to Dogubeyitz hospital

December 29 Asyegul Ozcan (9F) and Yusuf Ozcan (3M) develop symptoms

December 26 Fatma (15F), Hulya (12F), Ali Hasan Kocyigit (6M) develop symptoms

December 24 Kocyigits have Ozcan family over for dinner

December 18 Mehemet Ali
Kocyigit (14M) visits doctor with mild symptoms

December 16 Mehemet Ali
Kocyigit (14M) develops symptoms

Map

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