Paradigm Shift Intervention Monitoring
twitter
Commentary
US
Pneumonia and Influenza Death Rate Spikes to 8.89%
Recombinomics
Commentary 18:30
February 17, 2011
Earlier this season H3N2 was dominant, but levels of H3N2 have been declining, while H1N1 has been increasing. A recent report out of the UK indicated the failure rate for the H1N1 vaccine was approximately 50%, which was not a surprise because of the dominance of the sub-clade with S188T in the UK, including sequences which were identical to H1N1 isolates in the United States. This sub-clade has become dominant across the northern hemisphere, including the United States.
Many states are reporting widespread influenza activity, providing additional data supporting immunological escape from the H1N1 circulating last season, as well as the vaccine target for 2009 and the 2010/2011 season. Remarkably, this same outdated target, A/California/07/2009, was recommended by WHO today as the target for the northern hemisphere in 2011/2012.
As seen in the spike in the P&I data and the dominance of the S188T sub-clade, the WHO selection procedure for influenza vaccine targets continues to be hazardous to the world’s health.
Media link
Recombinomics
Presentations
Recombinomics
Publications
Recombinomics
Paper
at Nature Precedings