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Commentary
These isolates represent significant vaccine breakthrough. The sequences are from the sub-clade that emerged in early 2010. The first public sequence was A/Pennsylvania/02/2010, but this sub-clade has become dominant in the northern hemisphere and has been occasionally designated as a low reactor by various labs, including the CDC. A series of related sequences was also just released by the Air Force, which were also collected from vaccinated hosts. However, only three H3N2 isolates from the United States (1%) have been designated as low reactors by the CDC. Moreover, a second isolate from the Australia series, A/Townsville/87/2010, was not designated as a low reactor even though the HA sequence was identical to the subsequent sequence that was designated as a low reactor. Moreover, the recent recommendation to WHO was to leave the H3N2 target, A/Perth/16/2009 unchanged for the 2011/2012 flu season in the northern hemisphere, which is largely based upon the inconsistent and unreliable antigen characterization test. The data reveal fatal flaws in the vaccine selection procedure used by WHO and the CDC, wqhich continues to put the world’s population at risk. A/TOWNSVILLE/106/2010 Mossman A/TOWNSVILLE/105/2010 Thursday Island A/TOWNSVILLE/104/2010 Thursday Island A/TOWNSVILLE/102/2010 Horn Island A/TOWNSVILLE/100/2010 Wujal Wujal vaccinated A/TOWNSVILLE/98/2010 Hopevale A/TOWNSVILLE/97/2010 Thursday Island vaccinated A/TOWNSVILLE/93/2010 Bamaga A/TOWNSVILLE/92/2010 Thursday Island Vaccinated A/TOWNSVILLE/87/2010 Naprunum vaccinated A/TOWNSVILLE/86/2010 Cairns Media link Recombinomics
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