Suspect H5N1 Fatality in Sohag Egypt
Recombinomics Commentary 07:51
February 26, 2008
And the deputy confirmed that one of the conditions [suspected cases] were dead yesterday Friday [Feb 22] and calls Amaal Salah Qubaisy Al Sayed (34 years) is married and have a new child four months.
And Youssef added a saying "the doctor carried out immediately the direction by the patient himself to the central hospital of Tahta for a work that he radiated [X-ray] and analyses of a suspicion of the bird flu, and the doctor was not content with that, but for the reassurance more carried out its transfer of the doubt [of the suspected case] carried out its transfer to Tahta fevers that in front of it, and it was confirmed that it is the bird flu to a blood money from the common diagnosis from the doctors".
the doctor was not content with that, but went himself to Suhaj fevers with accompanying the patient by Tahta ambulance for their acceptance at in the morning, explaining that it has worked a report its referral to the Minister of Health and the concerned authorities took place until the horrible news came with the death of Mrs. on Friday 22/2/2008 at after the afternoon four and she translated from Suhaj fevers to the general hospital of Suhaj
And the deputy denounced the neglect that happened in the non taking of the sample the hospital of the fevers Suhaj from the patient and she at it at 2 in the morning at 4 after the afternoon!!
The above translation describes a fatal suspect H5N1 case in Sohag. The patient did not improve last week and after x-rays raised additional concerns of an H5N1 infection, she was transferred to from Tahta to Sohag, but died shortly after transfer and a sample for testing was not collected.
This case is in addition to the H5N1 confirmed case (4F) in Minyah. That case also had x-ray confirmed pneumonia and is hospitalized in Cairo.
The confirmed and suspect cases may be signaling a new wave of H5N1 infections in Egypt. Last year there was a spike in cases in March and April, but those cases were mild. Only one in 17 H5N1 confirmed cases died, in marked contrast to cases at the beginning of last season or this season when 11 of 12 confirmed patients died.
Recently release poultry sequences include Gharbiya-like sequences with receptor binding domain changes, V223I and M230I, as well as reversion to the original poly-basic cleavage site RERRRKKR.
Release of human HA and NA sequences, as well as poultry NA sequences from this season would be useful. In late 2007 four of the five confirmed patients died, yet no sequence data has been made public by NAMRU-3 or the CDC.
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