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Commentary

CDC Issues New Beta2c Coronavirus Guidance
Recombinomics Commentary 21:00
March 7, 2013

The CDC has put out an early release MMWR which updates the current situation for nCoVs.  Associated with the MMWR are guidance including a new case definition and travel updates.  These updates highlight the concentration of cases in the Middle East and request notification of PUI’s (person under investigation).

The new guidelines highlight symptomatic cases with recent travel to the Arabian Peninsula. 

It is worth noting that this notice coincides with the timing of the SARS-CoV international outbreak 10 years, which began at the Metropole Hotel on February 21, but the confirmation of the outbreak happened in March, as guests began appearing at hospitals in Hong Kong, Singapore, Hanoi, and Toronto.  That initial spread was followed by the spike in reported cases from mid-March through mid-May.

Although the current nCoV is beta2c and SARS CoV is beta2b, the similarities in the disease presentations are striking as is the high case fatality rate for adults age 40 and above.

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