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Commentary
G158E
pH1N1Transmission Between MN and IL Swine
Recombinomics
Commentary 12:50
May 14, 2010
The above data describing the spread of pH1N1 throughout swine herds in the Midwest increases concerns that more swine polymorphism will enter the human flu reservoir via additional swine to human infections. Similarly, the increases in infections in swine herds worldwide increase the evolution rate of pH1N1 and creates more opportunities for species jumps, including humans.
Recently released human sequences from India included an isolate with three newly acquire synonymous changes, and all three could be found on the same swine isolate from Hong Kong, identifying additional recombination between human pH1N1 and swine H1N2, providing additional data supporting swine flu reservoirs feeding human flu reservoirs. The 1918 pandemic sequences have alternating regions matching human and swine H1N1 sequences.
The increase spread of pH1N1 in swine herds worldwide continues to increase pandemic concnerns.
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