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Commentary

H7 G228S Raises H7N9 Pandemic Concerns NOT
Recombinomics Commentary 13:30
May 23, 2013

Both isolates had potentially functional amino acid sites related to mammal- or human-adapting substitution T189A, Q226L, and G228S (H3 numbering) in the receptor-binding site of hemagglutinin.

The above comments from a New England Journal of Medicine paper, Live-Animal Markets and Influenza A (H7N9) Virus Infection, cite the second key receptor binding domain change in H7, G228S in A/Nanjing/1/2013 and A/environment/Nanjing/2913/2013. 

However, Genbank released the sequences today and neither sequence has G228S. 

Both are wild type (G) at position 228.

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