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Commentary
2013 H3N2v
Cases Spread To Hancock
County Fair Indiana
Recombinomics
Commentary 21:00
July 4, 2013
29 pigs from the Grant and Hancock county fairs have tested positive for influenza.
The above comments from the Indiana State Department of Health describe 8 additional H3N2v cases as well as 17 additional swine infected with influenza. The initial four cases were from the Grant County fair (see map) and sequences from three of the cases have been released. As noted for the first sequence, A/Indiana/04/2013, the two additional sequences, A/Indiana/05/2013 and A/Indiana/07/2013 matched human 2012 H3N2v cases and all three sequences were closely related to each other, signaling clonal expansion. These cases from the Grant County fair represented the earliest report of H3N2v cases in the summer fair season. The cases from the Hancock County Fair (see map) also were prior to the earliest cases from prior years, increasing concerns that the number of cases in 2013 will be significantly higher than the record 309 confirmed cases reported for 2012.
Moreover, as noted above, at least one case was not linked to the two fairs and at least one additional case was not linked to attendance at either fair or a home farm, and is likely linked to human to human transmission.
The increase in cases is also suggested by additional May and June 2013 H3N2v swine sequences released through the USDA surveillance program which have the same constellation of genes seen in the 2012 and 2013 cases.
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