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Paradigm Shift Intervention Monitoring | Commentary Human H5N1 Indonesian Sequences Available at Los Alamos Recombinomics Commentary August 4, 2006 Yesterday Indonesia pledged to release the H5N1 human sequence sequestered in the WHO private database. Today the password protection on the sequences was removed and the sequences became publicly available. Analysis of the sequences can help determine origins and predict targets for vaccines. Orgins can be traced by monitoring informative polymorphisms. Below is one such series, showing the similarity between the various human isolates and relationship to other H5N1 bird flu sequences at Genbank or Los Alamos. ISDN136817 A/Feline/Indonesia/CDC1/2006 2006 H5N1 ISDN136812 A/Indonesia/CDC326/2006 2006 H5N1 ISDN136810 A/Indonesia/CDC326N/2006 2006 H5N1 ISDN136811 A/Indonesia/CDC326N2/2006 2006 H5N1 ISDN136813 A/Indonesia/CDC326T/2006 2006 H5N1 ISDN136814 A/Indonesia/CDC326T/2006 2006 H5N1 ISDN136815 A/Indonesia/CDC329/2006 2006 H5N1 ISDN136816 A/Indonesia/CDC357/2006 2006 H5N1 ISDN136908 A/Indonesia/CDC370/2006 2006 H5N1 ISDN136909 A/Indonesia/CDC370E/2006 2006 H5N1 ISDN137412 A/Indonesia/CDC370P/2006 2006 H5N1 ISDN137413 A/Indonesia/CDC370T/2006 2006 H5N1 ISDN181365 A/Indonesia/CDC523/2006 2006 H5N1 ISDN183297 A/Indonesia/CDC523E/2006 2006 H5N1 ISDN183305 A/Indonesia/CDC523T/2006 2006 H5N1 ISDN183313 A/Indonesia/CDC582/2006 2006 H5N1 ISDN140835 A/Indonesia/CDC594/06 2006 H5N1 ISDN140843 A/Indonesia/CDC595/06 2006 H5N1 ISDN140851 A/Indonesia/CDC596/06 2006 H5N1 ISDN140859 A/Indonesia/CDC597/06 2006 H5N1 ISDN140866 A/Indonesia/CDC599/06 2006 H5N1 ISDN183782 A/Indonesia/CDC599N/2006 2006 H5N1 ISDN183698 A/Indonesia/CDC610/2006 2006 H5N1 ISDN183706 A/Indonesia/CDC623/2006 2006 H5N1 ISDN183714 A/Indonesia/CDC623E/2006 2006 H5N1 ISDN183722 A/Indonesia/CDC624/2006 2006 H5N1 ISDN183730 A/Indonesia/CDC624E/2006 2006 H5N1 ISDN183738 A/Indonesia/CDC625/2006 2006 H5N1 ISDN183770 A/Indonesia/CDC625L/2006 2006 H5N1 ISDN183746 A/Indonesia/CDC634/2006 2006 H5N1 ISDN183754 A/Indonesia/CDC634P/2006 2006 H5N1 ISDN183762 A/Indonesia/CDC634T/2006 2006 H5N1 DQ497667 A/chicken/Dairi/BPPVI/2005 2005 H5N1 DQ497668 A/chicken/Deli Serdang/BPPVI/2005 2005 H5N1 DQ497651 A/chicken/Gunung Kidal/BBVW/2005 2005 H5N1 DQ497652 A/chicken/Kulon Progo/BBVW/2005 2005 H5N1 DQ497643 A/chicken/Magetan/BBVW/2005 2005 H5N1 DQ497648 A/chicken/Purworejo/BBVW/2005 2005 H5N1 DQ320928 A/chicken/Salatiga/BBVet-I/2005 2005 H5N1 DQ497665 A/chicken/Simalanggang/BPPVI/2005 2005 H5N1 DQ497669 A/chicken/Tarutung/BPPVI/2005 2005 H5N1 DQ497666 A/chicken/Tebing Tinggi/BPPVI/2005 2005 H5N1 DQ320933 A/chicken/Wajo/BBVM/2005 2005 H5N1 DQ497659 A/duck/Parepare/BBVM/2005 2005 H5N1 ISDN125873 A/Indonesia/5/05 2005 H5N1 ISDN136806 A/Indonesia/CDC287E/2005 2005 H5N1 ISDN136807 A/Indonesia/CDC287T/2005 2005 H5N1 ISDN136808 A/Indonesia/CDC292N/2005 2005 H5N1 ISDN136809 A/Indonesia/CDC292T/2005 2005 H5N1 DQ497662 A/chicken/Kupang-1-NTT/BPPV6/2004 2004 H5N1 DQ497663 A/chicken/Pangkalpinang/BPPV3/2004 2004 H5N1 DQ320930 A/chicken/Yogjakarta/BBVet-IX/2004 2004 H5N1 AY651372 A/Ck/YN/115/2004 2004 H5N1 DQ497707 A/goose/Vietnam/264/2004 2004 H5N1 DQ497647 A/quail/Boyolali/BPPV4/2004 2004 H5N1 DQ497649 A/quail/Yogjakarta/BBVet-IX/2004 2004 H5N1 AY651369 A/Dk/YN/6255/2003 2003 H5N1 AY651351 A/Ck/Hong Kong/3169.1/2002 2002 H5N1 Media Sources Phylogenetic Trees |
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