ECDC H3N2v Risk Assessment Is Still Fatally Flawed



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H1N1 Consulting Paradigm Shift Viral Evolution Intervention Monitoring Vaccine Screening Vaccine Development Expression Profiling Drug Discovery Custom Therapies Patents	Audio:Aug1 Aug7 Aug8 Aug16 twitter Commentary ECDC H3N2v Risk Assessment Is Still Fatally Flawed Recombinomics Commentary 12:30 August 22, 2012 As transmission of the disease is mainly related to direct contact with infected pigs, travellers to the affected states in the USA who have contact with pigs in farms or visit agricultural exhibitions may be at risk of being infected. In case they develop influenza-like symptoms after swine exposure, clinicians should consider and sample for the influenza A(H3N2)v viruses. The above comments from the August 20, 2012 ECDC risk assessment fails to address the heavy sample bias in the CDC data. The recent release of details of the USDA H3N2pM cases indicates that the data has already been made public at Genbank and the sequence data in H3N2pM reveals a dominance of the sub-clade found in the first 10 human cases in 2011. However, there have been no reported 2012 H3N2v cases involving this sub-clade in spite of widespread detection in swine in 2012. All of the 2012 H3N2v represent a novel sub-clade first reported in West Virginia in late 2011, which is rarely detected in H3N2pM. Thus, the above ECDC risk assessment is still fatality flaw because of the focus on swine to human transmission. Media Link Recombinomics Presentations Recombinomics Publications Recombinomics Paper at Nature Precedings

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