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Commentary

H3N2v Ohio Cases Increase to 107 in 25 Counties
Recombinomics Commentary 16:00
September 26, 2012

Ashland (1), Athens (8), Butler (17), Champaign (15), Clark (3), Fairfield (1), Franklin (4), Gallia (12), Greene (6), Hamilton (3), Henry (6), Huron (3), Jackson (1), Lake (1), Licking (2), Madison (1), Medina (1), Monroe (2), Montgomery (5), Morrow (1), Preble (3), Richland (2), Ross (7), Union (1), Warren (1).

The above list represents the September 26 tally of H3N2v cases confirmed in Ohio by the Ohio Department of Health (ODH).  The number of cases increased from 106 to 107, while the number of counties remained at 25. 

Montgomery County added the new case.

Although the increase in H3N2v cases has slowed dramatically, the detection of cases is still largely dependent on the monitoring of agricultural fairs.

The CDC has released 57 sets of H3N2v sequences from July/August collections and all matched the novel sub-clade first noted in 2011 at the West Virginia day care center.  The detection of this novel sub-clade in all recent collections, as well as the first 2012 isolate (A/Utah/10/2012), signal human transmission, which is also supported by the absence of any reported human cases with the H3N2v sub-clade detected in the first 10 cases in 2011.  This earlier sub-clade continues to be detected in recent (May, June, July, 2012) swine isolates.

Similarly, the recent paper on the 2011 Washington County fair cites 80 suspect cases based on ILI symptoms, highlighting the limitations of the CDC routine surveillance, which failed to detect any of these cases.

H3N2v continues to spread in humans in the US, which is largely missed by the current surveillance system.

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