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Commentary
Iowa H3N2pdm11
Surveillance Raises Pandemic Concerns
Recombinomics Commentary 07:30
November 29, 2011
The above comments from the CDC early release MMWR on the Iowa cluster, highlight differences between the 2009 pandemic involving H1N1pdm09, and the 2011 pandemic, involving H3N2pdm11 (aka trH3N2 w/ H1N1 M gene or S-OtrH3N2), The Iowa cluster involved three H3N2pdm11 confirmed cases (A/Iowa/07/2011, A/Iowa/08/2011, A/Iowa/09/2011), as well as two untested symptomatic family members (brother and father) of the index case who developed symptoms within 2 days of contact with the index case (3F, A/Iowa/07/2011). None of the above, or asymptomatic contacts, reported recent swine exposure, clearly signaling human transmission.
However, in spite of lab confirmation of this large cluster, the CDC is enhancing surveillance of those in the neighborhood of the cases, and ignoring the hundreds of influenza A positive samples which have been identified, but not sub-typed, throughoutt the country, but not sub-typed, including large numbers in Georgia and South Carolina (in Region 4), CDC’s location and neighborhood.
Instead of requesting additional samples from children user the age of ten, which account for 9 of the 10 H3N2pdm11 sequenced cases, the CDC again requested samples from patients with swine contact, To date the number of sequences from influenza A positive samples from patients under the age of 10 has been limited to 12, and 9 of the 12 have H3N2pdm2011.
Thus, after 75% of the sequences from children under the age of 10 have identified H3N2pdm11, the CDC limits expanded testing of ILI cases to a small neighborhood adjacent to the daycare center in Iowa.
The CDC’s denial of the 2011 pandemic continues to be hazardous to the world’s health.
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