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Commentary
WHO
Corrects Novel
Beta
Coronavirus Guideline Errors
Recombinomics
Commentary 15:00
November 30, 2012
Of the seven confirmed cases, five developed acute renal failure and three of these died. The remaining two confirmed cases had pneumonia that required intensive support, without renal failure, and recovered. Three of the seven confirmed cases and the one probable case all belong to the same family and were living in the same household.
The above comments (in red) are from the WHO updated guidelines (dated November 28) for testing cases which may be infected with the recently described novel betacornavirus, which were available at the WHO website yesterday morning (November 29). These comments were inconsistent with the November 23 WHO update, which cited two additional fatal cases (one confirmed and one awaiting testing) which increased the number of fatal cases to three including two from the same family – an AP report indicated both developed renal failure prior to death). These inconsistencies were noted yesterday (here and here).
Today, the WHO has corrected (in blue) the update to increase the number of fatalities to three (from one), and the number with renal failure to five (from four) - see bold above.
Last night CIDRAP had cited additional detail for the third confirmed cases, reported by the KSA MoH on November 4. A published paper noted that the case was a 45 year old male, who developed symptoms on October 9 and was on dialysis from October 15-22.
The correction to the WHO update removes the inconsistencies with these additional reports and the corrections highlight the similarities with clinical presenations and outcomes in the current cases and the SARS CoV cases in 2003.
However, release of the ages of the additional confirmed and probable cases, as well as the disease onset dates for the four family members (3 confirmed and 1 probable) in the Riyadh cluster, would be useful.
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