Fujian H5 Die-Off At Wiser Lake Washington



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H1N1 Consulting Paradigm Shift Viral Evolution Intervention Monitoring Vaccine Screening Vaccine Development Expression Profiling Drug Discovery Custom Therapies Patents	AudioOct16 Oct27 Nov3 Nov20 twitter Commentary Fujian H5 Die-Off At Wiser Lake Washington Recombinomics Commentary December 17, 2014 19:00 The northern pintail duck samples were collected by officials from the Washington Department of Fish and Wildlife following a waterfowl die-off at Wiser Lake, Washington, and were sent to the U.S. Geological Survey (USGS) National Wildlife Health Center for diagnostic evaluation and initial avian influenza testing. The U.S. Department of the Interior's USGS, which also conducts ongoing avian influenza testing of wild bird mortality events, identified the samples as presumptive positive for H5 avian influenza and sent them to USDA for confirmation. The gyrfalcon samples were collected after the falconer reported signs of illness in his birds. The above comments from a USDA update on Fujian H5 in Whatcom County, Washington provides additional detail on the OIE report on H5N8 in a pet falcon and an H5N2 report in a northern pintail, The pintail was from Wiser lake, while the falcon has been fed duck meat from a wild bird shot in the area. Additional reports indicated 3 pet falcons in Lynden have been H5N8 confirmed. The above comments suggest that more wild birds, in addition to the pintail may have been H5 confirmed. The pintail was H5N2 confirmed and is likely linked to Langley and Aldersgrove farms which were less than 10 miles to the north in British Columbia (see map). The OIE report described partial sequence data for the H5 and N8 from the falcon, which were consistent with recent H5N8 outbreaks in Germany, The Netherlands, England, Italy, and Japan (see map). The presence of two Fujian H5 serotypes leaves open the possibility that more serotypes will be identified since the H5N2 had an N2 from North American wild birds and many different N serotypes have bene reported in North America. Moreover, additional constellations may be seen for internal genes because the N5N2 had two additional internal genes derived from North American lineages. Therefore release of full sets of sequences from Canada and the United States will be useful. The above die-off may signal a limited immunity in wild birds for Fujian H5 (clade 2.3.4) which is the same in H5N2 and H5N8 as well as multiple serotypes in China including H5N1, H5N5, and H5N6. The reported H5N2 reassortant leaves open the possibility of more combinations of internal genes as well as concerns that the two Fujian H5 serotypes described above will migrate south an seriously affect poultry throughout North America in the near term. Media Link Recombinomics Presentations Recombinomics Publications Recombinomics Paper at Nature Precedings

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